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pentobarbital will decrease the level or effect of brexpiprazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Intently. Double brexpiprazole dose over 1-2 months if administered with a powerful CYP3A4 inducer.Observe Carefully (2)pentobarbital will decrease the level or effect of buprenorphine, prolonged-a